Use PikiStrips to make comics from your own photos using standard sets of panel layouts. You can choose to have from 1 to 9 panels, and for each one, there are multiple layout designs. The content from the panels can be uploaded images from your computer or ones found by searching in flickr. In each panel you can apply PhotoShop-like effects to images (blur, canvas, watercolor) and then add speech bubbles and other "goodies" (clip art like hearts, etc).

Your creations can then be sent to a store for on demand printing as a t-shirt, mouse pad, coffee mug, or gift bag.